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Second, although this analysis included 45 studies with a fairly large sample size, the low incidence of thyroid events resulted in a wide confidence interval that reduced the certainty of our findings

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"That's how we'll get real answers about prevalence and causality, which social media data alone can't provide." "These are signals, not conclusions but I do think it's always worth talking to your doctor about anything unexpected you're experiencing while on a new medication, even if you're not sure if it's related," he advised

10.1007/s11892-019-1178-6 40 RussellR.CarneseP

[DOI] [PubMed] [Google Scholar] 31.Labouesse MA, Stadlbauer U, Weber E, Arnold M, Langhans W, Pacheco-Lpez G

For context, many peptides show strong receptor activation in vitro but fail to produce clinical effects because they cannot be delivered at effective concentrations in living organisms