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Discussing known effects and theoretical risks The most common side effects with GLP-1RAs are gastrointestinal (GI)

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People with faster baseline metabolism may experience more dramatic digestive slowdowns, while those with naturally slower digestion often adapt more easily

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Protein intake deserves particular attentionadequate protein (1.0-1.2 g/kg body weight daily during active weight loss) supports lean muscle mass preservation, which contributes to metabolic heat production