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Alert your PlexusDx care team right away if you notice persistent abdominal symptoms, as they may indicate the need to switch to an alternative therapy or adjust your current protocol

[19] Sudden increases may worsen bloating, so incremental adjustments over 2-3 weeks are advisable

UK patients with obesity should engage with existing NICE-recommended services, including licensed medicines such as orlistat or semaglutide 2.4 mg (Wegovy)

Precautions Rapid weight loss can accelerate muscle loss

To explain the differences between the metabolic effects of subcutaneous WAT and visceral WAT, it has been suggested that visceral WAT releases metabolites into the portal vein to impact hepatic metabolism, unlike subcutaneous WAT that bypasses the portal vein [75]

However, as long as you keep your portions small, use a part-skim mozzarella or goat and feta cheese, and embrace alternative crusts like cauliflower crust, many people make successfully eat pizza in moderation when they are on Ozempic