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"With GLP-1 medications reducing appetite significantly, we're not just aiming for a calorie deficit anymore

The update also reflects a broader shift in how medicines are being distributed, recognising that patients increasingly expect and benefit from direct-to-patient models, particularly for treatments relating to sensitive conditions such as obesity

A slower climb often beats a fast escalation that ends with skipped meals, dehydration, and stopping the peptide entirely

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they found GLP-1RAs did not significantly change eGFR (standard mean difference [SMD] 0.07 mL/min/1.73m 2

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