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55 , 56 Given that GLP1RA drugs likely impact the metabolic homeostasis and energy equilibrium of the target tissue, conducting singlecelltypespecific metabolic profiling is instrumental to uncover the molecular mechanisms by which ligand binding to GLP1R induces alterations in the target cells of endometrial tissue

Among patients with T2DM, although three patients had access to a high dose of semaglutide, no significant reduction in background medication was observed (Table 2)

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This may be related to electrolyte imbalances, reduced protein intake, or the metabolic stress of significant caloric restriction

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