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Greater knowledge of the mechanisms of fat fuel partitioning that underlie the metabolic and behavioral actions of GLP-1RAs could also provide a roadmap for the development of new or adjunctive pharmacological or other strategies for treating obesity and associated metabolic diseases," they conclude

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Efficacy and safety of semaglutide 2.4 mg in the Japanese subgroup of the ESSENCE study

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An understanding of their effects on BP may help provide an explanation for the ability of GLP-1a to influence cardiovascular (CV) events in ongoing event-driven CV trials.