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These may include: Nausea, vomiting or diarrhoea (most common early on) Constipation Fatigue Mild increases in heart rate (similar to changes seen with GLP-1 medicines) Side effects were more frequent at higher doses (8 mg and 12 mg), but still rated mild to moderate overall

cracking down on sales of the drug to Americans?, Canadian Broadcasting Corporation (2023) Drug shortage report for Ozempic, Drug Shortages Canada (2024) Notice: Recommendations while Ozempic and other GLP-1 agonists are in shortage, Health Canada (2023) Ozempic, Cetaphil makers warn of impact from Trump tariffs, Bloomberg (2025) Doctor tied to thousands of Ozempic prescriptions in B.C

Second, cerebrospinal fluid has its own way of passing into the brain

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