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Amongst, overweight and obese patients defined by BMI in 2024 (58.9% [95% CIs 53.3-64.2%] female [182/309], median [IQR] age 56.6 [46.2-66.1]) GLP 1RA use has increased from 3.2% (10/309 [95% CIs 1.8-5.9%]) to 13.6% (42/309 [95% CIs 10.2-17.9%] [p=7.1x10-6])

"It is concerning that, in some cases, people can simply go online and order these kinds of medications," researchers said.

Tirzepatide should be avoided in patients with gastroparesis, as GLP-1 receptor agonists delay gastric emptying and can significantly worsen symptoms