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Excess fat in the abdominal area, called visceral fat, contributes to major causes of death and disability, such as heart attacks, strokes, high blood pressure, some cancers, fatty liver disease, and type 2 diabetes

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For example, one of the most notable trials on the subject is the ELAD trial, which stands for Evaluating Liraglutide in Alzheimer's Disease. This 12-month RCT reported that liraglutide improves cognitive function and MRI volume in the temporal lobe and whole cortex, suggesting a potential benefit in treating Alzheimer's [21]

Quick Answer: GLP-1 medications may contribute to reflux-like symptoms through delayed gastric emptying, though acid reflux is not consistently reported as a primary adverse effect in clinical trials