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While these trials were not specifically designed to assess joint pain, patients with obesity-related joint pain who achieve significant weight loss through GLP-1 therapy often report improved mobility, reduced need for analgesics, and enhanced ability to engage in physical activitycreating a positive cycle of further weight management and joint health

M., Gregg, E
Cardiovasc Diabetol 21(1):232 Hu Y et al (2022) Cost-effectiveness analysis of 4 GLP-1RAs in the treatment of obesity in a US setting

[DOI] [PMC free article] [PubMed] [Google Scholar] 274.Wadden T.A., et al

However, the body views energy conservation as a survival priority
