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Wang HW, Mizuta M, Saitoh Y, Noma K, Ueno H, Nakazato M

Microdosers lose 7-13 pounds over 6-12 weeks

doi: 10.1172/jci.insight.136136

"We identified that this type of hypoglycaemia is associated with the dysregulation of serotonin levels in the blood, a hormone that, in addition to controlling mood, is also capable of stimulating the secretion of the hormones insulin and GLP-1 in the body," explained Rafael Ferraz-Bannitz, who conducted the research during an internship abroad

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We show that GLP-1R stimulation in DR is sufficient to induce hypophagia and increase electrical activity of the DR serotonin neurons