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GLP-1 drugs like Ozempic have transformed weight management, but concerns around muscle loss, bone density, dampened desire, and dependency are growing

However, the triagonist failed to enhance insulin secretion in islets lacking both Glp-1r and Gipr and upon treatment with the GLP-1 receptor-specific antagonist exendin-3 (939)

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reductions vs GLP-1 RAs ranged from 1.68 kg with tirzepatide 5 mg to 7.16 kg with tirzepatide 15 mg
