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Activation of plasma membrane TGR5 receptors in enteroendocrine cells by bile acids is known to regulate gastrointestinal secretion and motility and glucose ...

A recent cohort study has illuminated significant disparities in the fulfillment of prescriptions for glucagon-like peptide-1 receptor agonists (GLP-1RAs), a class of medications pivotal in managing

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Today, we announced our investigational glucagon/GLP-1 dual receptor agonist achieved key measures of success at 48 weeks in our IMPACT Phase 2b trial and recent interactions with the FDA have resulted in alignment on the parameters for a registrational Phase 3 trial

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There is a unique opportunity for collaboration across specialties to raise awareness around the multiple benefits of GLP-1 RAs and determine the best care pathway to treat patients with PAD. With the ongoing PAD amputation and obesity epidemics, there is an opportunity to establish partnership and open communication between vascular surgeons and weight loss clinics to determine if a patient could benefit from GLP-1 RAs. i Molina CS, Faulk JB