glp 1 agonists moa Mechanisms of GLP-1 Receptor Agonist-Induced Weight Loss: A Review of Central and Peripheral Pathways in Appetite and Energy Regulation Mechanism of action of GLP-1

These inflammatory molecules can worsen diabetic complications, including nerve damage

SGLT-2, sodium-glucose cotransporter-2

[DOI] [PubMed] [Google Scholar] 257.Mochida T., Hira T., Hara H

GLP-1 Receptor Agonists Use and Impact on Concurrent Esophagogastroduodenoscopy and Colonoscopy The literature available on the outcomes of patients undergoing EGD with concurrent colonoscopy while on GLP-1 RAs is very scarce

Hepatic fat reduction, in particular, may not fully reverse immediately, giving the liver additional time to recover from years of steatotic damage

Blocking this pathway could be a promising therapeutic strategy for DPN by curbing the inflammatory response and potentially preventing further nerve damage [76]