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Disease burden and epidemiological trends of chronic kidney disease at the global, regional, national levels from 1990 to 2019

doi: 10.1038/s41591-024-02996-7

Tirzepatide potently activates the GLP-1R signalling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R

Findings are preliminary, and more research is needed to understand this risk
Joe Pazona and co-host Cat Williams discuss GLP-1 agonists, often referred to as miracle weight loss drugs, in a new episode of the Balls Deep podcast
On the other hand, the incidence of new or worsening nephropathy was significantly decreased in the semaglutide group compared to placebo
