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10-year follow-up of diabetes incidence and weight loss in the diabetes prevention program outcomes study Diabetes prevention program research

However, a meta-analysis on the clinical trial of new hypoglycemic drugs showed that the risk of AKI caused by GLP-1RA was neutral and higher than that of another hypoglycemic drug, sodium-glucose co-transporter 2 inhibitor (SGLT2i) ( Due to the low incidence rate of AKI, the above studies failed to summarize the general characteristics of adverse reactions

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Both organizations now recommend a treatment approach that is centered on the patient's comorbidities, particularly atherosclerotic cardiovascular disease (ASCVD), heart failure (HF), and chronic kidney disease (CKD)

How often should I monitor health markers (BP, glucose, lipids)

Gradual tapering under provider guidance minimizes these risks