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Retatrutide is the most powerful weight loss peptide in clinical development right now, a triple agonist that hits GLP-1, GIP, and glucagon receptors simultaneously

When activated, these receptors send satiety signals to your brain and slow the rate at which food moves through your stomach

Notably, tirzepatide can decrease exposure to oral contraceptives, requiring the use of backup contraception for 4 weeks after initiation and after each dose increase

You do not need to twist your body to reach the thigh, making it simple to inject even without a mirror

Cigna also announced a specialized GLP-1 pharmacy, which will soon go live for patients

Make the medication switch first