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This review highlights the interconnected metabolic and neuronal mechanisms in Parkinsons disease encompassing -synuclein pathology, sirtuin imbalance, and disrupted insulin signaling role in PD and explores incretin and phytomolecules molecule based therapies, often utilized for type 2 diabetes management as complementary multi-target neuroprotective strategies

Betacell replacement therapies that use stemcellderived, fully differentiated, insulinproducing islet cells are in phase 1/2 clinical trials [142, 143, 144, 145]

It is not a drug and does not replicate the pharmacological effect of prescription GLP-1 medications

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Doctors stress that patients must stop Ozempic right away and get emergency help if they suspect pancreatitis

Semaglutide was associated with an improvement in ankle-brachial indices a test that compares the blood pressure in the ankle with the blood pressure in the arm to check blood flow in lower limbs