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Unlike restrictive diets that rely heavily on willpower, tirzepatide may help reduce the constant hunger signals that often make weight loss difficult

The importance of insulin regulation and metabolic control has led to recruitment of genes in this pathway in venom function in various species

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According to NICE guidance (NG28), GLP-1 receptor agonists like Ozempic may be considered for adults with type 2 diabetes when glycaemic targets are not met on other therapies, particularly when weight loss would be beneficial or in people with established cardiovascular disease where agents with proven cardiovascular benefit are preferred