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In early 2026, the FDA publicly announced its intent to take enforcement action against certain mass-marketed non-FDA-approved GLP-1 products

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These results support the hypothesis that GLP-1 RAs may exert neurologic benefits beyond glycemic control. Kornelius added

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Baseline thyroid function tests, including TSH and free T4, should be documented before initiating treatment, with the patient ideally in a euthyroid state on stable levothyroxine replacement

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