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Compounding pharmacies arent the only makers of off-brand versions of Novo Nordisks Wegovy and Eli Lillys Zepbound

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From JAMA Internal Medicine: This JAMA patient page covers #GLP1 weight-loss medications, focusing on food craving reduction, blood glucose control, dietary strategies, exercise for muscle retention, and lifestyle changes to prevent weight regain

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In this issue of Diabetologia, Kang et al (DOI: 10.1007/s00125-012-2776-x ) provide evidence that in addition to glucotoxicity, lipotoxicity also affects incretin receptor expression and signalling in insulin-secreting cells and isolated islets