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In addition, rodent studies demonstrating thyroid C-cell hyperplasia and tumors led to class warnings and contraindications in susceptible populations

However, skepticism is still warranted regarding their indiscriminate use

Gallego R

Seino, Y., Fukushima, M., Yabe, D

Regular follow-up appointments and adherence to monitoring protocols are essential to ensure the safe and effective use of these medications

When adverse events like this occur, compounding pharmacies are not obliged to report these events to the FDA , something that original manufacturers are required to do, which could lead to a significant underreporting reflected in data