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WangMDHuangYZhangGPMaoLXiaYPMeiYWet al
The interaction isn't necessarily dangerous, but it requires dosing adjustments and close monitoring

When patients lose significant weightparticularly rapidlythe reduced mechanical loading on the skeleton can trigger bone resorption

Fineman MS, Mace KF, Diamant M, et al

Those with a prior history of kidney stones have a higher baseline risk, and Wood noted that several other factors may increase vulnerability

(2) -mannosidase hydrolyzes the -1,4-mannosidic bond at the non-reducing ends of the MOS fragments, releasing mannose [23]
