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Description
Lancet 2023;402:529-544

Recent research indicates that adipose-derived extracellular vesicles (AdEVs) are pivotal in intercellular communication and may influence metabolic dysregulation related to obesity, cancer advancement, and systemic inflammation

For instance, GLP-1 reduces blood pressure by lowering the secretion of atrial natriuretic peptide (ANP) [36]
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Instead, its a full-scale transformation of how Americans eat, shop, and care for themselves

if high risk (2.67 or age-adjusted threshold), referral to specialist care or arrangement of liver elastography is recommended

Together, these two studies elucidate pathways that inform strategies coupling GLP-1R signaling to control of body weight in patients with diabetes or obesity