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Nonetheless, rigorous clinical trials are needed to establish the safety, efficacy, and optimal protocols for these combination regimens in MASLD patients ( 5 Conclusion In conclusion, the evolving landscape of MASLD treatment underscores the significant therapeutic promise of GLP-1RAs and dual or triple receptor agonists

Thats a risky trade-off

Brand-name Wegovy costs $1,349 per month without insurance, while PlexusDx compounded semaglutide starts at $149 per month
Some people do better at moderate doses (1 to 1.7 mg) with excellent tolerability than at maximum dose (2.4 mg) with persistent side effects

Keep an eye on the progression of diabetic retinal disease

Lets embrace curiosity and shared decision-makingand build the evidence base together
