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Signaling in Monocyte Adhesion and Foam Cell Formation GLP-1 agonists also target macrophages to prevent the formation of lipid-laden foam cells, a hallmark of atherosclerosis

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Without insurance, Zepbound can cost anywhere from $299 to over $1,000 per month

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serious but rare side effects may involve allergic responses

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Canagliflozin (SGLT2i) contributes to decreased inflammation, extracellular matrix turnover, and fibrosis (300 mg/day decreased plasma levels of TNF receptor 1, IL-6, matrix metalloproteinase 7, and fibronectin 1 after 2 years of follow-up) [93]

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doi: 10.1212/WNL.0000000000002461

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The recent surge in GLP-1 prescriptionsmany prescribed for off-label usehas only added to the financial burden

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