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The enrollment of patients was initiated in June 2021 and will end in May 2023

Despite substantial mechanistic and preclinical evidence indicating neuroprotective effects, translating these findings into clinical benefits has proven challenging

As a result, excess glucose is excreted through the urine, leading to a reduction in blood glucose levels

How do we create the optimal plan for each patient? Research should also further explore the psychological impact of weight-loss treatment, including the risk of eating disorders, say those involved

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doi: 10.1172/JCI134018 250 XiongXLiX