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JAMA Intern Med 2013;173:534-9.ArticlePubMed 60

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Importantly, no studies have yet addressed long-term neurodevelopmental outcomes in exposed offspring, a critical gap given the rising use of these agents among reproductive-age women

Several treatment options are available to address the changes in the face and restore a more youthful appearance
The use of bland moisturizers and gentle over-the-counter cleansers is recommended

This biological framework supports the hypothesis that androgen status may influence skeletal muscle resilience during sustained weight reduction, as illustrated in Figure 2