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4,5 TABLE 1 provides a summary of key characteristics of currently available injectable GLP-1 receptor agonists

Preliminary results suggest that, unlike calorie restriction, semaglutide, tirzepatide, and RYGB weaken the appetite feedback control circuit resulting in an extended period of weight loss prior to the plateau

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These findings may also help explain why the risk of pancreatitis appears to be of greater magnitude during the first 6 months of treatment

Together, they provide a solid foundation for long-term success

A single dose should not be divided