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Each plays a role, allowing for personalized strategies that address the complexity of obesity, says Dr
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Patients with moderate renal insufficiency received 50 mg daily of Januvia and those with severe renal insufficiency or with ESRD on hemodialysis or peritoneal dialysis received 25 mg daily

Fellow pharma powerhouse Roche has also jumped into the oral obesity arena with the $2.7 billion acquisition of Carmot Therapeutics in December 2023, giving it access to CT-388 and CT-868, both of which are dual agonists of the GLP-1 and GIP receptors with best-in-class potential for obesity, Roche said at the time

Heterogeneity test was shown in S7-S9 Tables and funnel plots of publication bias were shown in S2 Fig C-F