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Acta Cardiol 78(5):552564 Mahapatra MK, Karuppasamy M, Sahoo BM (2022) Semaglutide, a glucagon like peptide-1 receptor agonist with cardiovascular benefits for management of type 2 diabetes
An exploratory DEXA analysis of the STEP 1 trial found that semaglutide produced a 9.7% reduction in total lean body mass over 68 weeks alongside a 19.3% reduction in total fat mass, meaning fat was lost at roughly twice the rate of lean tissue
Variability in study designs, sample sizes, durations, and outcome measures complicates direct comparisons between the findings
Anal Biochem 399:190195
Protect from heat and light High temperatures also damage semaglutide
