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Food and Drug Administration announced on January 13 that it has requested Novo Nordisk and Eli Lilly to remove references to suicide and suicidal thoughts from the labels of GLP-1 medications Saxenda, Wegovy, and Zepbound
Animal model studies have suggested that GLP-1RAs may cause pancreatitis and exocrine dysplasia, but in the large RCTs and a meta-analysis, GLP-1RAs did not increase the risk of pancreatitis or pancreatic cancer [82,83]
GCGR activation drives effects not produced by GLP-1R/GIPR agonism alone: Hepatic fat mobilisation , GCGR activation in the liver promotes fatty acid oxidation and ketogenesis
Atypical anorexia nervosa Patients with atypical anorexia nervosa, a subtype of other specified feeding and eating disorder (OSFED), meet all criteria for anorexia nervosa except that, despite significant weight loss, their weight remains within or above the normal range (American Psychiatric Association, 2013)
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Stent-retriever thrombectomy after intravenous t-PA vs
