gip/glp-1 agonist Targeting GLP-1, GIP & GCG in Obesity and Type 2 Diabetes Research glp 1 and gip glp

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NZ: Writing original draft

Conclusion In patients with prediabetes, GLP1 RA initiation was associated with a lower risk of requiring additional glucoselowering therapy, compared with metformin

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doi:10.1111/j.1365-2982.2007.01079.x Schirra J, Nicolaus M, Woerle HJ, Struckmeier C, Katschinski M, Gke B

Previous physiological studies have shown that both GIP (113116) and GLP-1 (117) act in concert with glucose to enhance insulin gene transcription, mRNA stability, insulin biosynthesis, and insulin secretion