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THE DIABETES CONTROL AND COMPLICATIONS TRIAL In 1993, all controversy regarding the impact of glucose control and vascular complications was dramatically answered with the publication of the Diabetes Control and Complications Trial (DCCT)(5)

The Lancet Psychiatry [Internet]

Common adverse effects of tirzepatide include nausea (approximately 24% in obesity trials), constipation (21%), vomiting (18%), and fatigue

Where do PBMs fit in

Clinical trial data may not reflect typical real-world experiences

found that the protective effect of dulaglutide on learning and memory impairment might be the result of reducing the hyperphosphorylation of tau and neurofilament proteins in a PI3K/AKT/GSK3 signaling pathway-dependent manner (48)