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These compounds reduce central neuroinflammation by lowering interleukin (IL)-1, IL-6, and tumor necrosis factor-alpha (TNF-), and limiting oxidative stress ( On the other side, current trends in precision psychiatry aim to classify subpopulations of patients with inflammatory depression, characterized by elevated markers of inflammation, increased glucose and lipid levels, neurovegetative symptoms, anxiety or irritability, and suicidal ideation (Wessa et al., 2026)
Extensive research and clinical trials have demonstrated that GLP-1 medications are generally safe for both short-term and long-term use
She hopes that may soon change, however
10.1016/j.isci.2024.109784 [DOI] [PMC free article] [PubMed] [Google Scholar] 26
The actual published clinical evidence
