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Many patients find that continuing treatment through the adjustment period leads to symptom resolution without medication changes

Some patients find their ideal dose at 1 mg or 1.7 mg if these levels provide good results with fewer side effects

Combining these effects during active infection makes it harder to distinguish medication side effects from illness symptoms, complicates hydration status monitoring, and may prevent adequate caloric intake needed for immune function

Additionally, these medications enhance glucose-dependent insulin secretion from pancreatic beta cells whilst suppressing inappropriate glucagon release, thereby improving glycaemic control in individuals with type 2 diabetes

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