risks of glp 1 agonists Long-Term Effects GLP-1 Medications: What You Should Know Frontiers | Exploring the multifaceted
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2024;51(1) doi: 10.1007/S11033-024-09793-Y

The strong gastric emptying delay produces significant nausea and constipation requiring aggressive management, but most users adapt by weeks 12-16 with proper titration
In terms of key secondary outcomes, mean changes from baseline in body weight at week 26 were -1.2 kg, -2.2 kg, and -3.1 kg for semaglutide 3 mg, 7 mg, and 14 mg, respectively

While nausea typically resolved over time, diarrhea (observed in 5% of our cohort) tended to persist when present, though it was manageable in most cases with antidiarrheal agents

The countrys focus on innovative, evidence-based treatments supports broad physician adoption of GLP-1 therapies for obesity