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Non-obese diabetic mice aged 7 weeks were treated for 1 week with JD-5037, then euthanised

-1 Incretins have an important role in glucose homeostasis, regulation of appetite, energy expenditure and immunity

However, its clinical benefits are limited by its short half-life, which is less than 2 min because of its small size and rapid enzymatic inactivation by dipeptidyl peptidase IV

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Combining intermittent fasting with tirzepatide requires careful timing and medical oversight
