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Dose Optimization and Genetic Factors in Nausea Response Not all patients tolerate the standard dose escalation schedule
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And in the extension phase out to 104 weeks, the highest dose arm exceeded 30% weight reduction

The BCPNN analysis further validated these findings, demonstrating that female patients had higher risks of long-term treatment-related adverse reactions, whereas male patients experienced more acute adverse events in the short term

From a clinical standpoint, barriers may be removed by: Educating patients on atrial fibrillation, its complications, its treatments, and its outcomes
