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Description
Tirzepatide (TZP), a dual GLP-1/GIP receptor agonist, is recognized for its potent glycemic and weight-lowering effects, yet its influence on hepatic mitochondrial dynamics in diabetes remains unclear

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No severe orthostatic hypotension was observed in either the tirzepatide or placebo groups.

After 1 year, liraglutide/placebo recipients switched to liraglutide 2.4mg, then 3.0mg (based on 20-week and 1-year results, respectively)
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