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Patients with cardiovascular (CV) risk, for instance, FDCs planned with sitagliptin and metformin or empagliflozin have shown superiority versus monotherapy on the grounds of treatment efficacy in clinical trials [29]

doi: 10.3389/fendo.2023.1132004 [DOI] [PMC free article] [PubMed] [Google Scholar] 13.Zhu R, Chen S

In conclusion, GLP-1 improves cognitive function by engaging multiple signaling pathways, including CREB, PI3K/Akt, mTOR, and SIRT1

Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress
