gip glp 1 tirzepatide Effects of tirzepatide, a dual and GLP-1 receptor agonist, on blood pressure, cardiac function, and sympathetic nervous system in stroke-prone spontaneously hypertensive rats Microdosed Tirzepatide

The takeaway: While you cant keep taking GLP-1s, you have good options

GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimers disease

Eur J Heart Fail (2017) 19(1):6977

J Nucl Med Technol

Acknowledgements Graphical Abstract, Figure 1, and Figure 2 were created using Biorender

In a real-world situation, suppression of both ingestive (eating food already available) as well as motivated behavior (willingness to put in effort to obtain food) is required for effective reduction in food intake and therefore also weight loss, and based on results from animal models GLP-1R agonists can suppress both, and more potently in females