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How Tirzepatide Works Tirzepatide activates both GIP and GLP-1 receptors, with a stronger emphasis on GIP receptor activation

Beyond these, in the pre-clinical space, over 25 candidates have been disclosed, but our analysis of patents, company disclosures, and early-stage publications identifies nearly 70 additional undeclared pre-clinical programs

The August 2023 announcement of topline results was followed in November 2023 by a presentation of detailed results7, which revealed a statistically significant reduction in non-fatal myocardial infarction of 28% and smaller reductions in cardiovascular death and non-fatal stroke which were not statistically significant over the length of the trial (up to five years)

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Consult your healthcare professional before use if you have a medical condition, are taking medication, are using a GLP-1 receptor agonist, or are under medical supervision

For the 40% of American adults with obesity, glucagon-like peptide-1 receptor agonists, or GLP-1 drugs, may offer hopebut the cost can put them out of reach for many patients