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The most common side effects reported in the Eli Lilly trials were mild-to-moderate gastrointestinal issues such as nausea and vomiting

A recent study review concluded that while green tea extract supplementation had no significant effects on the two appetite-regulating hormones, leptin and ghrelin, it did help reduce body fat percentage and BMI

however, a treatment gap remains between the therapeutic success of these molecules and the outcomes achieved with bariatric surgery

Significant fat loss can reduce peripheral estrogen production, which may affect symptoms in postmenopausal women not on HRT

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Age Ageing 48(1):1631 [DOI] [PMC free article] [PubMed] [Google Scholar] 3.Xu Y, Hu T, Shen Y, Wang Y, Bao Y, Ma X (2023) Association of skeletal muscle mass and its change with diabetes occurrence: a population-based cohort study