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Conclusions GLP-1RAs had a neutral effect on the composite cardiovascular outcomes but reduced composite kidney events in the patients with advanced DKD compared with DPP-4is.

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We review recommendations that have been published to date, and consider the best availablebut currently limitedevidence from large observational studies and the DARE-19 randomized control trial

Back in 1990, an endocrinologist named John Eng was
