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Description
Summary The development of the long-acting GLP-1 analogs liraglutide and semaglutide, using albumin binding to extend the half-life, represents a significant advance in GLP-1-based therapies
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Especially, the emergence of sodium-glucose cotransporter-2 inhibitor (SGLT2i) can be cited as the primary factor for this change

doi: 10.1186/s12872-015-0003-7