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The reason storage discipline matters more here than for a single-use peptide is arithmetic: because one vial spans several once-weekly doses over potentially a month, the solution has to hold potency across that entire window

Funding This work was supported by National Institutes of Health Grants R01-DK-114663, P01-HL-62222 and endowed McIntyre Professorship to K.P

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It's a testament to the importance of clinical observation, patient advocacy, and the willingness to think outside conventional paradigms

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40 However, the improvement in peak VO 2 was within the margin of measurement error and was not accompanied by a corresponding improvement in the 6MWT distance or quality of life, so this finding needs to be investigated further