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However, following weight loss, the skin may struggle to contract efficiently, resulting in sagging and a prematurely aged appearance

Do not recap (recapping causes needle-stick injuries)

Starting BMI and weight loss goal Metabolic health, including prediabetes, diabetes, insulin resistance, fatty liver, or PCOS Blood pressure, heart rhythm history, anxiety, and sleep issues Reflux or GERD history Preference for pills versus injections Side effect tolerance, including nausea, constipation, insomnia, or jitteriness Insurance coverage, self-pay cost, and pharmacy access History of bariatric surgery or weight regain after surgery Bottom line The right plan is the one you can tolerate, afford, and follow while your progress and safety are monitored over time

Eating smaller, more frequent meals, chewing food thoroughly, and gentle walking after meals may also reduce belching and gas

People on the highest dose of orforglipron lost on average around 10% of their baseline body weight, for instance, compared to the 2.5% average weight loss seen in those taking a placebo

If you were on 10 mg injectable, start at approximately 4 mg daily sublingual