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Restarting the medication helped restore some protection, but only partially, showing that discontinuation leaves a lasting scar. Healio previously reported that the discontinuation of GLP-1 receptor agonists was tied to weight regain and higher risks for some adverse pregnancy outcomes like gestational diabetes and preterm delivery

An important factor behind Ultomiris growing appeal is its longer dosing interval every eight weeks versus every two for Soliris

iScience 2021, 24

This means that there may be effects early on that result in the loss of more water, glycogen, etc

An investigational oral GLP-1 (orforglipron) is in late-stage development and may eventually offer an easier-to-take pill option, but it isnt yet approved