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Major cardiovascular outcome trials and real-life observations have proven that glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs), regardless of structural GLP-1 homology, exert clinically relevant cardiovascular protection

In a double-blind clinical trial, individuals taking semaglutide for GLP-1 weight loss in Santee, SC dropped 14.9% of their body weight over 68 weeks.